What is the primary role of the liver in lactic acid metabolism?

The primary role of the liver in lactic acid metabolism is to convert lactic acid back to pyruvic acid. This process is part of the Cori cycle, which helps to recycle lactate produced by anaerobic respiration in muscles. When muscles are active and oxygen levels are low, they convert glucose into lactic acid to generate energy. This lactic acid is then transported to the liver, where it can be converted back into pyruvic acid through a process called gluconeogenesis. Once in the form of pyruvic acid, it can enter the Krebs cycle for further energy production or be used to produce glucose, which can then be sent back to the muscles for energy during subsequent periods of activity. This conversion is crucial because it helps in managing and reducing lactic acid buildup, contributing to the regulation of blood pH and supporting sustained muscular activity.